- Younger brother of actors Joey Lawrence and Matthew Lawrence.
- His father is of Italian descent and his mother has English and Northern Irish ancestry.
- He directed two movies that he wrote himself called "Money Plane" and "Mistletoe Mixup". Both movies featured his brothers Matthew and Joey.
- When he was born Brandon Tartikoff (the president of NBC, who knew the Lawrence family thru Joey and Matthew on Gimme a Break! (1981) and other work for NBC) sent flowers to the hospital, and, as a joke, an acting contract for newborn Andy.
- Plays "Jason" on United States of Tara (2009). (April 2009)
- Uncle to older brother Joey's three daughters: Charleston "Charli" Lawrence, Liberty Grace Lawrence and Dylan Rose Lawrence.
- He is filming a movie in Texas (September 2004)
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