At the beginning of the film when Wyatt Earp is preparing for a shave, the lather is yet to be applied by the barber. A second after the gunshot strikes the mirror, Earp's entire chin is lathered, even though the barber is still preparing to apply it.
When Wyatt is playing poker, Chihuahua puts her leg up on a
chair showing her dark stockings. A few minutes later, when Wyatt catches her signaling the gambler, he pulls her outside and pushes her in a horse-trough and she's no longer wearing stockings.
When Clementine looks around Doc's room, Wyatt admires a picture of her, which in medium-long shot is clearly a full-length photograph of a woman. When the camera shows a close-up of the photograph, it is a head and torso shot of a woman.
Before Doc begins to operate on Chihuahua, without anesthesia, a cloth is placed in her mouth and she's told to "bite real hard." A moment later, when the scene has cut to a longer shot, and Doc has started, we hear Chihuahua cry out "Oh ma!" She couldn't have spoken with the cloth in her mouth.
When Chihuahua (Linda Darnell) sits on the bed of Doc Holliday (Victor Mature) at 56'17m into the movie, his left arm is raised, with his hand on his head as he is suffering from a headache. At 56'26m, it cuts to a mid-shot where Holliday's arm is at his side.
The movie shows James Earp killed (murdered) with his marker showing "born 1864 died 1882". However, James Earp was in fact born in 1841 and died in 1926 of natural causes. It was Morgan Earp who was murdered on 18 March 1882.
Doc Holliday did not die at the O.K. Corral. He died six years later from tuberculosis in a sanitarium in Glenwood Springs Colorado.
Wyatt Earp was never the town Marshal of Tombstone. Virgil Earp was.
The film shows Wyatt Earp (Henry Fonda) and John "Doc" Holliday (Victor Mature) meeting for the first time in Tombstone, AZ. In reality, Earp and Holliday were good friends by the time they came together in Tombstone, as they had met years earlier at Fort Griffin, TX.
In the film, "Old Man" Clanton (Walter Brennan) is shot and killed after the gunfight. In actuality, "Old Man" Clanton died in August 1881 - before the gunfight - and was not a principal in the gunfight itself or in the events immediately prior to the gunfight.
When "Indian Charlie" is shooting up the saloon, the original town marshal quits his job and surrenders his badge to the town mayor. Seconds later, Wyatt Earp approaches them to complain about his shave being interrupted. Wyatt turns to the now-badgeless ex-marshal, whom he had never seen before, and says "You're the marshal, ain't you?" One might think that Wyatt would have no way of knowing the ex-marshal, but he was just feet away from the marshal when he turned in his badge.
During the shootout, which supposedly occurs at sun up, the men's shadows are shorter than the men themselves, indicating the scene was shot much closer to noon.
Doc Holliday was supposed to be a surgeon in the movie. In fact, he was a dentist. On March 1, 1872, the Pennsylvania College of Dental Surgery in Philadelphia, conferred the degree of Doctor of Dental Surgery upon twenty-six men, one of whom was John Henry Holliday.